Laboratorio Interdisciplinario de Dinámica Celular y Nanoherramientas

Estudiantes motivados/as, becarios doctorales y postdoctorales interesados/as contactarse con el Dr. Oscar E. Pérez.

Resveratrol encapsulation in high molecular weight chitosan-based nanogels for applications in ocular treatments: Impact on human ARPE-19 culture cells. Buosi FS*, Alaimo A*, Di Santo MC, Elías F, García Liñares G, Castañeda Cataña MA, Acebedo SL, Spagnuolo C, Lizarraga L, Martinez KD, Pérez OE. J of Biol Macromol. 2020. *first authors

Biocompatibility analysis of high molecular weight chitosan obtained from Pleoticus muelleri shrimps. Evaluation in prokaryotic and eukaryotic cells.  Di Santo MC*, Alaimo A*, Domínguez Rubio AP, De Matteo R, Pérez OE. Biochem Biophys Rep. 2020. *first authors

Whey proteins-folic acid complexes: Formation, isolation, and bioavailability in a Lactobacillus casei model.  Rocío Corfield, Karina D. Martínez, Mariana C. Allievi, Patricio Santagapita, Florencia Mazzobre, Carolina Schebor, Oscar E. Pérez.  Food Structure. 2020. 26: 100162. 

Transcytosis of Bacillus subtilis extracellular vesicles through an in vitro intestinal epithelial cell model. Ana Paula Domínguez Rubio, Jimena Martínez, Marcos Palavecino, Federico Fuentes, Christian Miquel Sánchez López, Antonio Marcilla, Oscar Edgardo Pérez*, Mariana Piuri*. Sci Rep. 2020; 10: 3120. doi: 10.1038/s41598-020-60077-4. *both are corresponding authors

Quinoa does not contain prolamins. Comments on “Quinoa protein: Composition, structure and functional properties”, Dakhili et al. (2019). Hernán Burrieza, Axel Rizzo, Oscar Edgardo Pérez. Food Chem. 2020; 325: 1269310.1016/j.foodchem.2020.126934

Biological responses induced by high molecular weight chitosan administrated jointly with Platelet-derived Growth Factors in different mammalian cell lines. Mariana Carolina Di Santo, Agustina Alaimo, Sofía Lorena Acebedo, Carla Spagnuolo, Roberto Pozner, Oscar Edgardo Pérez. Int J Biol Macromol. 2020 May 8; 158:953-967.  doi: 10.1016/j.ijbiomac.2020.05.032

Combined Experimental and Molecular Simulation Study of Insulin-Chitosan Complexation Driven by Electrostatic Interactions. Cecilia Prudkin Silva; Oscar E Pérez; Karina D Martínez; Fernando Luis Barroso. J. Chem. Inf. Model. 2020, 60, 2, 854–865. doi.org/10.1021/acs.jcim.9b00814

Toxic effects of A2E in human ARPE-19 cells were prevented by resveratrol: a potential nutritional bioactive for age-related macular degeneration treatment. Agustina Alaimo; Carolina Di Santo; Ana Paula Dominguez Rubio; Gabriela Chaufan; Guadalupe García Linares; Oscar E. Perez. Arch Toxicol. 2020. 94(2):553-572. doi: 10.1007/s00204-019-02637-w.

Impact of Fat Replacement by Core-shell Microparticles on Set Type Yoghurts. Study of their physicochemical, textural, and microstructural properties. Yonaha, Maria Veronica; Martinez, Maria Julia; Allievi, Mariana Claudia; Coluccio Leskow, Federico; Perez, Oscar Edgardo. Current Nutrition & Food Science. 2019. 14(1). doi: 10.2174/1573401314666180503154304

Betanin loaded nanocarriers based on quinoa seed 11S globulin. Impact on the protein structure and antioxidant activity. Jimena H Martínez; Francisco Velázquez Duarte; Hernán Burrieza; Karina D Martínez; Ana Paula Domínguez-Rubio; Cristina Dos Santos Ferreira; María Del Pilar Buera; Oscar E Pérez. Food Hydrocolloids. 2018. 87. doi: 10.1016/j.foodhyd.2018.09.016.

Proposed molecular model for electrostatic interactions between insulin and chitosan. Nano-complexation and activity in cultured cells. Cecilia Prudkin-Silva; Jimena H Martínez; Karina D Martínez; Edith Farías; Federico Coluccio-Leskow; Oscar E. Perez. Colloids and Surfaces A Physicochemical and Engineering Aspects. 2018. 537. doi: 10.1016/j.colsurfa.2017.10.040

Proteins as Nano-Carriers for Bioactive Compounds. The Case of 7S and 11S Soy Globulins and Folic María. Emilia Ochnio, Jimena H Martínez, Mariana C Allievi , Marcos Palavecino, Karina D. Martínez, Oscar E. Pérez. Polymers. 2018. 10(149). doi: 10.3390/polym10020149

Lactobacillus casei BL23 Produces Microvesicles Carrying Proteins That Have Been Associated with Its Probiotic Effect

Ana Paula Domínguez Rubio; Jimena Hebe Martínez; Diana Martínez Casillas; Federico Coluccio Leskow, Mariana Piuri; Oscar Edgardo Pérez. Frontiers in Microbiology. 2017. 8:178. doi:  10.3389/fmicb.2017.01783

Strategy for Foaming Improvement of Whey Protein Concentrates by Addition of hydroxypropylmethylcellulose and Heating: Relation with Interfacial Properties. Oscar E Pérez; Karina D Martínez; Cecilio Carrera-Sánchez; Juan Miguel Rodríguez Patino. Nutrition and Food Technology. 2017. 10.16966/2470-6086.141

PICT 2017-1683. Nanoencapsulación de compuestos bioactivos con impacto biomédico y nutricional. Enfoque “Ómico” desde el diseño hasta su efecto. Investigador responsable: Dr. Oscar E. Pérez. 

PICT Start Up 2015-3866. Quitosano argentino para el desarrollo de nanocápsulas de tipo core-shell destinadas a la protección y liberación controlada de bioactivos. Investigador responsable: Dr. Oscar E. Pérez. 

UBACyT 20020150100079BA. Bionanoencapsulación de compuestos de relevancia nutricional y biomédica para su protección, direccionamiento y liberación controlada. Investigador responsable: Dr. Oscar E. Pérez.